Cyp7b1 genecard
WebCYP7B1 Antibodies Antibodies that detect CYP7B1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry and ELISA. These antibodies target CYP7B1 in Human, Mouse and Rat samples. Our CYP7B1 polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. WebCYP7B1 is a member of the cytochrome P450 superfamily of monooxygenases, involved in the metabolism of cholesterol, neurosteroids, and other lipids. It is responsible for …
Cyp7b1 genecard
Did you know?
WebSep 24, 2024 · CYP7B1 cytochrome P450 family 7 subfamily B member 1 Gene ID: 9420, updated on 24-Sep-2024 Gene type: protein coding Also known as: CP7B; CBAS3; SPG5A See all available tests in GTR for this gene Go to complete Gene record for CYP7B1 Go to Variation Viewer for CYP7B1 variants Summary WebIn humans, CYP27A1 mutations cause cerebrotendinous xanthomatosis, suggesting that only mice can compensate for the loss of alternative bile acid synthesis. In line with this, Cyp7b1 knockouts are also apparently normal, whereas human CYP7B1 mutations lead to a congenital bile acid synthesis defect in children or spastic paraplegia in adults.
WebCholesterol 7alpha-hydroxylase (CYP7A1) is the initial and rate-determining enzyme in the "classic" pathway of bile acid synthesis. An "alternative" pathway of bile acid synthesis is … Webhypothesis currently under investigation is that CYP7B1 inactivates neurosteroids in brain. There is as yet no evi-dence that pregnenolone or dehydroepiandrosterone accu-mulates in CYP7B1 knock-out mice; consequently, the impor-tance of CYP7B1 in clearing these steroids from the brain and body versus other enzymes that utilize these substrates ...
WebCYP7B1 Antibodies Antibodies that detect CYP7B1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry and … WebApr 13, 2024 · Abstract Deficiency in cytochrome P450 (CYP) 7B1, also known as oxysterol 7α-hydroxylase, in humans leads to hereditary spastic paraplegia type 5 (SPG5) and in some cases in infants to liver disease. SPG5 is medically characterized by loss of motor neurons in the corticospinal tract.
WebOct 16, 2009 · The CYP7B1 cytochrome P450 enzyme hydroxylates carbons 6 and 7 of the B ring of oxysterols and steroids. Hydroxylation reduces the biological activity of these …
WebMar 9, 2024 · Setchell et al. (1998) determined that the CYP7B1 gene contains 6 exons. The positions of the 5 introns are identical to those of the CYP7A1 gene. Mapping By … selected marketsWebMar 21, 2024 · GeneCards Summary for CYP7B1 Gene CYP7B1 (Cytochrome P450 Family 7 Subfamily B Member 1) is a Protein Coding gene. Diseases associated with … CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1) is a Protein … Complete information for LINC00251 gene (RNA Gene), Long Intergenic Non … selected mat select angularWebFeb 11, 2024 · Seventy percent of the world’s internet traffic passes through all of that fiber. That’s why Ashburn is known as Data Center Alley. The Silicon Valley of the east. The … selected meWebThe CYP7B1 gene is a member of the cytochrome P450 gene family. Enzymes produced from cytochrome P450 genes are involved in the formation and breakdown of various … selected maxi dressWebThe CYP7B1 gene encodes an evolutionarily conserved P450 and is found in the genomes of organisms ranging from humans to the Japanese fire-bellied newt to the fungus Aspergillus niger. The human gene spans … selected mathWebFeb 5, 2024 · CYP7B1 provided by HGNC Official Full Name cytochrome P450 family 7 subfamily B member 1 provided by HGNC Primary source HGNC:HGNC:2652 … selected media not available wwiseWebApr 11, 2024 · Cyp7b1 Depletion Impairs Cold-Induced Bile Acid Synthesis and Affects Brown Adipose Tissue Responses Once activated by cold, BAT has been shown to internalize substantial amounts of lipids and glucose, thus attenuating hyperlipidemia ( Bartelt et al., 2011) and hyperglycemia ( Stanford et al., 2013 ). selected media gmbh berlin