Lysosome-associated membrane glycoprotein 2
WebFeb 15, 2024 · Lysosome-associated membrane glycoprotein 2 Short names LAMP-2; Lysosome-associated membrane protein 2 Alternative names CD107 antigen-like family member B LGP-110 1 publication LGP-96 1 publication Lysosomal membrane glycoprotein type B ( LGP-B) CD Antigen Name CD107b Gene names Name Lamp2 … WebBLAST of Lysosome-associated membrane glycoprotein 2 vs. UniProt/SwissProt Match: sp P11438 LAMP1_MOUSE (Lysosome-associated membrane glycoprotein 1 OS=Mus musculus OX=10090 GN=Lamp1 PE=1 SV=2) HSP 1 Score: 65.0846 bits (157), Expect = …
Lysosome-associated membrane glycoprotein 2
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The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b.When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C-terminal sequence: in the luminal domain, the transmembrane domain, and the cytoplasmic tail. The … See more Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid hydrolases … See more LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous … See more WebLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, …
WebPharos : Target Details - LAMP2 Targets Ligands About Tutorials lightbulb feedback Protein Classes help help No PANTHER Classes or DTO Classes found Expression Data (0 Tissues) help help tutorial lightbulb No expression data found Protein Sequence and Structure help help Residue Counts Protein Sequence Find Targets by Sequence search WebLysosome-associated membrane protein (LAMP2) cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, …
WebJul 19, 2012 · The family of lysosome-associated membrane proteins (LAMP) comprises the multifunctional, ubiquitous LAMP-1 and LAMP-2, and the cell type-specific proteins DC-LAMP (LAMP-3), BAD-LAMP (UNC-46, C20orf103) and macrosialin (CD68). ... Structure of human lysosomal membrane glycoprotein 1. Assignment of disulfide bonds and … WebLysosome-associated membrane glycoprotein 2A LAMP2A up- or downregulation, and its presence or absence in the lysosomal membrane, enhances or decreases CMA activity, respectively. 34 , 35 The LAMP2A mRNA transcript is generated from alternative splicing of lysosome-associated membrane glycoprotein 2 ( LAMP2 ) pre-mRNA; this splicing …
WebMar 9, 2024 · lysosome-associated membrane glycoprotein 2, CD107 antigen-like family member B, lysosomal membrane glycoprotein 2, lysosomal membrane glycoprotein type B GeneRIFs: Gene References Into Functions LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development.
WebOct 15, 2024 · LYSOSOME-ASSOCIATED MEMBRANE PROTEIN B; LAMPB LYSOSOMAL MEMBRANE GLYCOPROTEIN, 110-KD; LGP110 CD107B HGNC Approved Gene Symbol: LAMP2 Cytogenetic location: Xq24 Genomic coordinates (GRCh38): X:120,426,148-120,469,349(from NCBI) Gene-Phenotype Relationships gatwick to zante flight timeWebThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the membrane … gatwick to vienna flightsWebGene ID: 118461668, updated on 29-May-2024. Summary Other designations. lysosome-associated membrane glycoprotein 2-like gatwick track arrivalsWebFuruno K, Ishikawa T, Akasaki K et al. Morphological localization of a major lysosomal membrane glycoprotein in the endocytic membrane system. J Biochem 1989;106:708–16. ... Silverstein RL, Febbraio M. Identification of lysosome-associated membrane protein-2 as an activation-dependent platelet surface glycoprotein. Blood 1992; 80:1470–75. daydreamer neck pillowWebIt houses enzymes involved in oxidation reactions, which produce hydrogen peroxide (H 2 O 2 \text H_2 \text O_2 H 2 ... The inner membrane of a lysosome is made up of proteins with an 'unusually' large number of carbohydrate groups attached to them. This prevents the breaking down of the proteinaceous membrane, ergo protecting them from the ... daydreamer outsourcingWebFeb 6, 2013 · LIMP-2, also known as SCARB2 belongs to the CD36 family of scavenger receptors 31 and spans the lysosomal membrane twice, with the N- and C-terminus located in the cytosol and a highly glycosylated loop within the lysosomal lumen (Figure 2 ). gatwick trains disruptionWebNov 28, 2024 · Peak areas of 4 formerly N-glycosylated peptides, belonging to 4 distinct glycoproteins (Adipocyte plasma membrane-associated protein, Periostin, Cathepsin D, and Lysosome-associated membrane glycoprotein 2) turned out to be significantly increased in subjects affected by PCa compared to controls (Fig. 4). gatwick train line map